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Ketamine is a medication primarily used for starting and maintaining anesthesia. It is an amnestic, meaning it causes loss of memory. Ketamine is a dissociative anesthetic and hallucinogen, which means it distorts perceptions of sight and sound and produces feelings of detachment from the environment and self. It has been used in human and veterinary medicine.
Ketamine was first synthesized in 1962 by Calvin L. Stevens while working for Parke-Davis. It was initially studied as an intravenous anesthetic agent but was found to have too many side effects for this use. Ketamine was then studied as a possible alternative to phencyclidine (PCP), which was also being researched as an anesthetic at the time. Unlike PCP, ketamine did not produce the same degree of sedation or dissociation from reality, making it more suitable for use as an anesthetic agent.
Ketamine is now approved for use as a human anaesthetic agent in many countries around the world. In the United States, it is approved for use in both humans and animals by the Food and Drug Administration (FDA). Ketamine is typically administered intravenously or intramuscularly but can also be given orally, rectally, or intraperitoneally.
The main effect of ketamine is to produce anesthesia, meaning loss of feeling and awareness. The degree of anesthesia produced by ketamine is dose-dependent; higher doses result in deeper levels of anesthesia. Ketamine also has some hallucinogenic effects at high doses, producing visual and auditory hallucinations as well as a sense of detachment from one's surroundings (known as "dissociation"). These effects are more likely to occur when ketamine is used recreationally rather than medically.
Ketamine has a number of other potential medical uses beyond its primary role as an anaesthetic agent. Low doses of ketamine have been shown to be effective in treating depression, anxiety, post-traumatic stress disorder (PTSD), chronic pain, migraines, and even some forms of addiction such as alcoholism . Ketamine has also been studied as a possible treatment for strokes and other brain injuries . However, more research is needed before any definitive conclusions can be drawn about the efficacy of these potential uses for ketamine .
Can you die from Ketamine overdose?
It is also known as Special K and is a popular party drug. Some people use it recreationally for the dissociative effects it produces. When misused, ketamine can cause serious health problems, including death. Overdosing on ketamine can be fatal. The drug slows down your breathing and heart rate, which can lead to cardiac arrest or respiratory failure. Ketamine also increases your risk of developing ulcers and bladder problems. Long-term abuse of ketamine can lead to permanent damage to your kidneys, liver, and brain. If you or someone you know has overdosed on ketamine, call 911 immediately.
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What is Ketamine syndrome?
Ketamine is a powerful anesthetic that is sometimes used illegally as a party drug. It can cause dissociation, hallucinations, and out-of-body experiences. People who abuse ketamine often take it repeatedly over a short period of time, which can lead to ketamine syndrome. Ketamine syndrome symptoms include: - Severe agitation - Hallucinations - Delirium - High blood pressure - Rapid heart rate - Muscle tremors or spasms
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What are the long term effects of taking Ketamine?
However, it has also been found to be effective in treating long-term pain, depression, and anxiety. Though ketamine is generally considered safe, there are some potential long-term effects that may occur with its use. The most common long-term effect of ketamine is tolerance. Tolerance occurs when the body becomes used to the drug and requires larger doses to achieve the same desired effect. Tolerance typically develops over time and can lead to dependence if ketamine is used regularly. Dependence occurs when the body adapts to the presence of ketamine and needs it to function normally. Those who are dependent on ketamine may experience withdrawal symptoms when they attempt to stop using the drug. These symptoms can include agitation, insomnia, nausea, and vomiting. Another potential long-term effect of ketamine is damage to the urinary tract. Ketamine can cause inflammation and scarring of the bladder and kidneys which can lead to kidney problems or failure down the line. ItвЂ™s important to drink plenty of fluids while taking ketamine to help prevent this from happening. Finally, regular use of ketamine can result in cognitive impairment. This means that those who take ketamine may have trouble thinking clearly, concentrating, or remember things correctly. This effect is usually temporary but can become permanent with heavy use.
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Why do Ketamine cause constipation?
However, in recent years, it has also been used to treat humans for conditions such as pain and depression. While ketamine is generally safe and effective, one of the most common side effects is constipation. There are a few reasons why ketamine may cause constipation. First, ketamine can cause the muscles in the gastrointestinal tract to relax. This can slow down or even stop the movement of food through the digestive system, leading to constipation. Another reason why ketamine may cause constipation is that it can increase the amount of time it takes for the stomach to empty. When food stays in the stomach for too long, it can harden and become difficult to pass. Lastly, ketamine can reduce the production of mucus in the intestine. Mucus helps keep stool moist and soft, making it easier to pass. Without enough mucus, stool can become dry and hard, making constipation more likely. If you experience constipation while taking ketamine, there are a few things you can do to help relieve your symptoms. Drink plenty of fluids and eat fiber-rich foods to help keep your stool soft. You may also want to try over-the-counter laxatives or enemas if home remedies donвЂ™t seem to be helping. If your constipation is severe or doesnвЂ™t improve with treatment, call your doctor
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How much is a 100 mg Ketamine?
Occasionally, it is also used as a dissociative recreational drug. When used in this way, it produces hallucinations and feelings of euphoria. The effects of ketamine vary depending on the dose. At lower doses, ketamine produces a mild dissociative state, characterized by dream-like visuals and auditory hallucinations. At higher doses, ketamine can cause profound dissociation, characterized by complete detachment from reality and out-of-body experiences. Ketamine is typically sold as a powder or liquid. The most common way to use ketamine recreationally is to snort it, although it can also be injected or taken orally. The effects of ketamine last for around 30-60 minutes when snorted, and up to 2 hours when injected. How much is a 100 mg Ketamine? A 100 mg dose of Ketamine would cost approximately $10USD if purchased on the street or online.
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How many days can you go without Ketamine?
When used recreationally, it is usually insufflated (snorted) or injected.3 Ketamine's effects last approximately 1-2 hours when taken orally or nasally and 2-6 hours when injected.4 The duration of effect is dependent on several factors including dosage, route of administration, frequency of use, and individual physiology.5 If ketamine is used too frequently, tolerance will develop. This means that higher doses will be needed to achieve the same effect as before.6 Tolerance typically develops within 3-14 days of regular use.7 Once tolerance has developed, it can take up to several weeks for it to return to pre-tolerance levels.8 Withdrawal symptoms are rare with ketamine use but can occur if the drug is discontinued suddenly after heavy, prolonged use.9 Symptoms of ketamine withdrawal include irritability, agitation, anxiety, sleep disturbance, and cravings for the drug.10 These symptoms are typically mild and self-limiting, resolve within 1-2 weeks without treatment; however in some cases they may be more severe and require medical intervention.11 It is difficult to determine how long someone can go without ketamine as there are many individual factors that come into play. For example, someone who uses ketamine infrequently may be able to go longer without it than someone who uses it daily.12 In general though, most people would start to experience withdrawal symptoms within a few days of discontinuing use if they had been using regularly.13
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What are the side effects of Ketamine in elderly?
It can also be used to treat pain and other conditions. When used as an anesthesia, ketamine can produce dissociation, a state in which a person feels disconnected from their surroundings and their own body. This feeling can last for several hours after the drug has worn off. While some people may enjoy this dissociative state, others may find it confusing or unsettling. In addition, ketamine can cause other side effects, including: Elevated blood pressure Increased heart rate Nausea and vomiting Dizziness and lightheadedness Blurred vision Confusion and disorientation Ketamine is generally considered safe when used as directed by a medical professional. However, there are some potential risks associated with its use, especially in elderly patients. These risks include an increased risk of falls, confusion, and delirium. Elderly patients should be closely monitored if they are given ketamine.
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